Apoquel® 5.4 mg Box of 100 film coated tabs

Apoquel® 5.4 mg — Effective Control for Canine Itch and Allergic Dermatitis

Apoquel® 5.4 mg (oclacitinib maleate) is a veterinarian-prescribed oral medication specifically formulated to provide rapid and reliable relief from pruritus (itching) associated with allergic dermatitis in dogs. Developed by Zoetis, Apoquel offers a targeted mechanism of action that reduces the inflammatory signals responsible for itching while preserving normal immune function. It is suitable for short-term control of acute flares and for long-term management under veterinary supervision.

Key Benefits

• Rapid onset: Clinical studies demonstrate itch reduction within hours and marked improvement within 24 hours for many dogs.
• Targeted action: Selectively inhibits Janus kinase (JAK) pathways that mediate itching and inflammation rather than broadly suppressing the immune system.
• Improved quality of life: Reduces scratching, biting, and licking — helping skin heal and preventing secondary infections.
• Long-term management: Can be used as a maintenance therapy under veterinary guidance with fewer steroid-related adverse effects.
• Easy administration: Film-coated tablets that can be given with or without food and are often accepted when hidden in treats.

What Apoquel 5.4 mg Contains

Each tablet contains 5.4 mg oclacitinib (active ingredient) along with inert excipients that ensure tablet stability and palatability. This strength is commonly used for medium-sized dogs; veterinarians will choose the appropriate tablet strength and dosing frequency according to the dog’s weight, clinical condition, and response to therapy.

How Apoquel Works

Apoquel is a selective Janus kinase (JAK) inhibitor. JAK enzymes transmit signals from cytokines involved in inflammation and pruritus. By inhibiting these JAK pathways, Apoquel reduces the production and activity of inflammatory mediators that trigger itching and allergic responses in the skin. This focused mechanism provides effective symptom control while minimizing broad immune suppression commonly associated with corticosteroids.

Typical Dosage and Administration

Dosage must be prescribed by a veterinarian. A common regimen is:

• Initial control phase: Twice daily (every 12 hours) for up to 14 days to rapidly reduce pruritus and allow the skin to begin healing.
• Maintenance phase: Once daily dosing thereafter, adjusted by the veterinarian based on clinical response.

Tablets may be administered with or without food. If the dog refuses the tablet, it can be concealed in a small amount of food or a soft treat. Do not split tablets unless specifically instructed by your veterinarian.

Indications

Apoquel is indicated for the control of pruritus associated with allergic dermatitis, including:

• Atopic dermatitis
• Flea-allergic dermatitis (as part of an overall flea control program)
• Food-related allergic reactions (as determined by a veterinarian)

Safety Information & Side Effects

Apoquel has been evaluated in clinical studies and is generally well tolerated. Common, typically mild side effects may include:

• Transient vomiting
• Diarrhea
• Reduced appetite
• Lethargy or temporary tiredness

Most side effects are self-limiting. Serious adverse events are uncommon but can occur. Prior to starting Apoquel, inform your veterinarian of any pre-existing conditions (e.g., infections, history of malignancy, liver or kidney disease) and provide a complete medication history. Apoquel should not be used in breeding, pregnant, or lactating dogs unless specifically directed by a veterinarian.

Contraindications and Precautions

• Apoquel is not recommended for dogs with known hypersensitivity to oclacitinib or any tablet excipients.
• Use caution when dogs have serious infections; immunomodulatory therapy can affect infection control.
• Prioritize veterinary supervision for dogs with pre-existing conditions or those receiving concurrent immunosuppressive drugs.

Monitoring and Veterinary Follow-Up

Regular follow-up with the prescribing veterinarian is important. Periodic physical examinations and, if advised, laboratory testing (e.g., blood counts, biochemical panels) help ensure safety and optimal dosing during extended use. If new symptoms appear or if the dog’s condition worsens, contact the veterinarian promptly.

Why Choose Apoquel?

Pet owners and veterinarians often select Apoquel because it combines rapid relief of itching with a targeted mechanism that reduces many steroid-associated risks. It is an effective component of a comprehensive dermatologic plan that may include allergen identification, topical therapy, flea control, and nutritional support.

Product Presentation

This listing is for Apoquel 5.4 mg film-coated tablets. Please ensure the product is dispensed by a licensed veterinarian and used strictly according to the prescription and instructions provided.

FAQ

Q: How soon will my dog improve?

A: Many dogs show measurable reduction in itching within 4–24 hours; full improvement of skin lesions may take days to weeks depending on severity.

Q: Can Apoquel be combined with other treatments?

A: Yes, when directed by a veterinarian. Apoquel is often used as part of a multi-modal treatment plan (topicals, flea control, hypoallergenic diets, or allergen-specific therapies).

Q: Is a prescription required?

A: Yes. Apoquel is a prescription medication; consult your veterinarian for diagnosis and dosing.

Important Notice

This description is provided for informational purposes and does not replace professional veterinary advice. Always consult a licensed veterinarian for diagnosis, treatment options, and prescription decisions for your pet. If you have questions about Apoquel 5.4 mg, side effects, interactions, or appropriate dosing for your dog, please speak to your veterinarian before administering any medication.